Publications

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in Acute Myeloid Leukemia.

Published in Blood, 2022

S. Goswami, R. Mani, J. Nunes, C.-L. Chiang, K. Zapolnik, E. Hu, F. Frissora, X. Mo, L. A. Walker, P. Yan, R. Bundschuh, L. Beaver, R. Devine, Y.-T. Tsai, A. Ventura, Z. Xie, Z. Xie, M. Chen, R. Lapalombella, A. Walker, A. Mims, K. Larkin, C. Bennett, M. Phelps, E. Hertleine, G. Behbehani, S. Vasu, J. C. Byrd and N. Muthusamy. PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in Acute Myeloid Leukemia. Blood 139(9), 1340–1358 (2022). https://doi.org/10.1182/blood.2020010344

Robust transcriptional profiling and identification of differentially expressed genes with low input RNA sequencing of adult hippocampal neural stem and progenitor populations.

Published in Frontiers In Molecular Neuroscience, 2022

J. K. Denninger, L. A. Walker, X. Chen, A. Turkoglu, A. Pan, Z. Tapp, S. Senthilvelan, R. Rindani, O. Kokiko-Cochran, R. Bundschuh, P. Yan, E. D. Kirby. Robust transcriptional profiling and identification of differentially expressed genes with low input RNA sequencing of adult hippocampal neural stem and progenitor populations. Frontiers In Molecular Neuroscience 15:810722 (2022). https://doi.org/10.3389/fnmol.2022.810722

Teaching Python for Data Science: Collaborative development of a modular & interactive curriculum

Published in Journal of Open Source Education, 2021

M. Duda, K. L. Sovacool, N. Farzaneh, V. Nguyen, S. Haynes, H. Falk, K. L. Furman, L. A. Walker, R. Diao, M. Oneka, A. Drotos, A. Woloshin, G. Dotson, A. Kriebel, L. Meng, S. Thiede, S. Ramdas, Z. Lapp, and B. N. Wolford. Teaching Python for Data Science: Collaborative development of a modular & interactive curriculum Journal of Open Source Education 4(46), 138 (2021). https://doi.org/10.21105/jose.00138

The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis

Published in Cell Reports, 2021

N. S. Michki, Y. Li, K. Sanjasaz, Y. Zhao, F. Shen, L. A. Walker, W. Cao, C.-Y. Lee, and D. Cai. The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis. Cell Reports 35 (4), 109039 (2021). https://doi.org/10.1016/j.celrep.2021.109039

ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model

Published in Blood, 2019

C.-L. Chiang, S. Goswami, F. W. Frissora, Z. Xie, P. Yan, R. A. Bundschuh, L. A. Walker, X. Huang, R. Mani, X. Mo, S. Baskar, C. Rader, M. A. Phelps, G. Marcucci, J. C. Byrd, L. Lee, and N. Muthusamy. ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in CLL mouse model. Blood 134 (5) 432-444 (2019). https://doi.org/10.1182/blood.2018882290

Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function

Published in Scientific Reports, 2019

V. Saxena, J. Fitch, J. Ketz, P. White, A. Wetzel, M. A. Chanley, J. D. Spencer, B. Becknell, K. R. Pierce, S. W. Arregui, R. D. Nelson, G. J. Schwartz, V. Velazquez, L. A. Walker, X. Chen, P. Yan, D. S. Hains, and A. L. Schwaderer. Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function. Scientific Reports 9, 545 (2019). https://doi.org/10.1038/s41598-018-36921-z