Published in Neuroinformatics (in press), 2022
L. A. Walker*, J. S. Williams*, Y. Li, D. Roossien, N. S. Michki, and D. Cai. nGauge: Integrated and extensible neuron morphology analysis in Python. Neuroinformatics XXX (2022). https://www.biorxiv.org/content/10.1101/2021.05.13.443832v1
Published in Blood, 2022
S. Goswami, R. Mani, J. Nunes, C.-L. Chiang, K. Zapolnik, E. Hu, F. Frissora, X. Mo, L. A. Walker, P. Yan, R. Bundschuh, L. Beaver, R. Devine, Y.-T. Tsai, A. Ventura, Z. Xie, Z. Xie, M. Chen, R. Lapalombella, A. Walker, A. Mims, K. Larkin, C. Bennett, M. Phelps, E. Hertleine, G. Behbehani, S. Vasu, J. C. Byrd and N. Muthusamy. PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in Acute Myeloid Leukemia. Blood 139(9), 1340–1358 (2022). https://doi.org/10.1182/blood.2020010344
Published in Frontiers In Molecular Neuroscience, 2022
J. K. Denninger, L. A. Walker, X. Chen, A. Turkoglu, A. Pan, Z. Tapp, S. Senthilvelan, R. Rindani, O. Kokiko-Cochran, R. Bundschuh, P. Yan, E. D. Kirby. Robust transcriptional profiling and identification of differentially expressed genes with low input RNA sequencing of adult hippocampal neural stem and progenitor populations. Frontiers In Molecular Neuroscience 15:810722 (2022). https://doi.org/10.3389/fnmol.2022.810722
Published in Journal of Open Source Education, 2021
M. Duda, K. L. Sovacool, N. Farzaneh, V. Nguyen, S. Haynes, H. Falk, K. L. Furman, L. A. Walker, R. Diao, M. Oneka, A. Drotos, A. Woloshin, G. Dotson, A. Kriebel, L. Meng, S. Thiede, S. Ramdas, Z. Lapp, and B. N. Wolford. Teaching Python for Data Science: Collaborative development of a modular & interactive curriculum Journal of Open Source Education 4(46), 138 (2021). https://doi.org/10.21105/jose.00138
Published in Cell Reports, 2021
N. S. Michki, Y. Li, K. Sanjasaz, Y. Zhao, F. Shen, L. A. Walker, W. Cao, C.-Y. Lee, and D. Cai. The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis. Cell Reports 35 (4), 109039 (2021). https://doi.org/10.1016/j.celrep.2021.109039
Published in 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI), 2021
B. Duan, L. A. Walker, D. Roossien, F. Shen, D. Cai, and Y. Yan. Unsupervised Neural Tracing in Densely Labeled Multispectral Brainbow Images. IEEE 18th International Symposium on Biomedical Imaging (ISBI) 1122–1126 (2021). https://doi.org/10.1109/ISBI48211.2021.9433932
Published in Nature Communications, 2020
F. Shen, M. Harrington, L. A. Walker, H. J. Chen, E. S. Boyden, and D. Cai. Light microscopy based approach for mapping connectivity with molecular specificity. Nature Communications 11, 4632 (2020). https://doi.org/10.1038/s41467-020-18422-8
Published in Journal of Neuroscience Methods, 2020
S. A. Dizaji, L. A. Walker, and D. Cai. TraceMontage: a Method for Merging Multiple Independent Neuronal Traces. Journal of Neuroscience Methods 332, 108560 (2020). https://doi.org/10.1016/j.jneumeth.2019.108560
Published in Journal of Translational Medicine, 2020
L. A. Walker, M. G. Sovic, C.-L. Chiang, E. Hu, J. K. Denninger, X. Chen, E. D. Kirby, J. C. Byrd, N. Muthusamy, R. Bundschuh, and P. Yan. CLEAR: Coverage-based Limiting-cell Experiment Analysis for RNA-seq. Journal of Translational Medicine 18 (1), 63 (2020). https://doi.org/10.1186/s12967-020-02247-6
Published in Blood, 2019
C.-L. Chiang, S. Goswami, F. W. Frissora, Z. Xie, P. Yan, R. A. Bundschuh, L. A. Walker, X. Huang, R. Mani, X. Mo, S. Baskar, C. Rader, M. A. Phelps, G. Marcucci, J. C. Byrd, L. Lee, and N. Muthusamy. ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in CLL mouse model. Blood 134 (5) 432-444 (2019). https://doi.org/10.1182/blood.2018882290
Published in Scientific Reports, 2019
V. Saxena, J. Fitch, J. Ketz, P. White, A. Wetzel, M. A. Chanley, J. D. Spencer, B. Becknell, K. R. Pierce, S. W. Arregui, R. D. Nelson, G. J. Schwartz, V. Velazquez, L. A. Walker, X. Chen, P. Yan, D. S. Hains, and A. L. Schwaderer. Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function. Scientific Reports 9, 545 (2019). https://doi.org/10.1038/s41598-018-36921-z